| dc.description.abstract | Fucoxanthin is a carotenoid which currently gaining popularity as a function food
and pharmaceutical benefit. Previously, it was reported that the inhibitory activity of
13-cis and 13’-cis fucoxanthin isomers on cancer cell growth was stronger than that of
the all-trans form. An average amount between 1.70 to 7.89 mg/g d.w. of fucoxanthin
can be extracted brown seaweed of Sargassum species, which are naturally grown on
almost of Indonesia’s coast. While in 2019, the production of Sargassum has reached
to 1340 tons with value of 304,000 USD for alginate purpose. Therefore, a strategic
processing of the brown seaweed to produce highly valuable bioactive compound has
attracted our research group to study. Recently, our research group has successfully
developed simultaneous purification of fucoxanthin isomers by open-column and
high-performance liquid chromatography techniques. We developed the method
prior to study the effect of drying on the recovery of fucoxanthin and its isomers,
which have potential bioactivity and health benefits for humans. Here, our methods
will be presented and reviewed. | en_US |
