| dc.description.abstract | BACKGROUND: Coronavirus disease (COVID-19) has become a global pandemic and is confirmed worldwide to
cause a high mortality rates; as of the April 23, 2020, over 189,000 deaths have occurred in 2,700,800 COVID-19
cases. However, it appears that little consideration has been given to smokers and the users of tobacco-related
products relative to the impact of the virus on that particular cohort of patients.
AIM: The aim of the study was to commence a narrative review of research and academic articles of the severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) prevalence related to cigarette smoking and the consumption of
tobacco-related products.
METHODS: The study involved evidence-based publication searches on ProQuest and EBSCOhost databases
informed by a number of keywords. The additional data were obtained from relevant journals searched manually, as
well as following up references or primary articles. The search was conducted from April 23 to 24, 2020, adopting
the use of several terms, such as “tobacco use” AND “COVID”, “tobacco use” AND “SARS-CoV-2”, “smokers” AND
“COVID”, “cigarette” AND “SARS-CoV-2”, and “tobacco use” AND COVID-19 AND sars-cov-2.
RESULTS: Several studies (n = 8) confirmed that conventional smoking and electronic cigarette use correlated
with the decline of the human immune system and the feasibility of infection. The second group of evidence (n = 9)
explored higher Angiotensin-converting enzyme 2 among smokers, as the binding sites of SARS-COV-2.
CONCLUSION: Tobacco use among smokers and former smokers is significantly correlated to the decline in the status
of the human immune system and worsen the disease prognosis. In addition, smoking status is associated with a greater
likelihood of smokers being infected with SARS-COV-2; a condition that can further develop into coronavirus disease. | en_US |
